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What Are the Side Effects of Andrew Huberman Creatine? Examining the Science

4 min read

According to discussions on the Huberman Lab podcast, creatine is considered one of the most effective and safest supplements available for most healthy individuals. Concerns about what are the side effects of Andrew Huberman creatine? should be directed toward the general side effects of creatine monohydrate, as Huberman himself recommends this common, highly-researched form of the supplement.

Quick Summary

Andrew Huberman does not endorse a specific creatine brand, recommending the standard creatine monohydrate instead. Side effects are typically minimal for healthy users, primarily consisting of water weight gain and mild gastrointestinal issues. Concerns about kidney damage and hair loss are largely unproven or misrepresented.

Key Points

  • No Specific Product: There is no specific 'Andrew Huberman creatine' brand; he recommends standard creatine monohydrate.

  • Minimal Side Effects: For most healthy adults, creatine monohydrate has minimal side effects, especially with a consistent, non-loading dose.

  • Common Side Effects: The most common effects are mild gastrointestinal distress and water retention in muscles, which are often dose-dependent.

  • Debunked Myths: Concerns about hair loss and kidney damage have been widely debunked for healthy individuals.

  • Dose Dependent: Higher doses, such as those in a loading phase, increase the likelihood of side effects like stomach upset.

  • Hydration is Key: Proper hydration is essential when taking creatine to prevent potential dehydration-related issues like muscle cramps.

In This Article

Is There a Specific 'Andrew Huberman Creatine'?

First, it is important to clarify a common point of confusion: there is no single 'Andrew Huberman creatine' product. Throughout his podcasts, Dr. Huberman consistently recommends creatine monohydrate, the most researched, cost-effective, and evidence-based form of creatine available on the market. The side effects and benefits associated with his recommendations are therefore the same as those associated with creatine monohydrate in general.

Common and Mild Side Effects of Creatine

For most healthy adults, creatine is generally well-tolerated, especially when taken at the standard daily dose of 3-5 grams. The most frequently reported and mildest side effects include:

Gastrointestinal Distress

Some individuals may experience gastrointestinal issues such as stomach cramps, bloating, or diarrhea, particularly during an initial loading phase or when taking higher doses (e.g., 15-25 grams per day). This can often be mitigated by:

  • Taking a lower, consistent daily dose of 3-5 grams instead of a loading phase.
  • Splitting the daily dose into smaller amounts taken throughout the day.
  • Taking creatine with food to improve digestive tolerance.
  • Using a high-quality creatine monohydrate, such as Creapure, which uses a cleaner manufacturing process.

Weight Gain from Water Retention

Creatine works by drawing water into the muscle cells, which increases muscle cell volume. This can lead to a slight increase in body weight, which is often misinterpreted as fat gain. It is important to note that this is water weight stored within the muscles themselves, not subcutaneous bloating, and is generally considered a normal part of the process of increasing muscle creatine stores. This effect is not harmful and can contribute to the appearance of fuller muscles.

Dehydration (Misconception)

Some people mistakenly believe that creatine causes dehydration or muscle cramps. The opposite is often true, as creatine improves cellular hydration by pulling water into the muscles. However, because creatine increases the demand for water within your muscles, it is crucial to increase your overall fluid intake to stay properly hydrated. Experiencing muscle cramps or dizziness is more likely a symptom of inadequate hydration during intense exercise rather than a direct side effect of creatine itself.

Potential but Largely Debunked Side Effects

Hair Loss

The idea that creatine causes hair loss by increasing dihydrotestosterone (DHT) levels is a common but largely unsupported myth. While a single, older study showed a marginal increase in DHT, experts like Dr. Kyle Gillette and Andrew Huberman have discussed this on the Huberman Lab. They point out that creatine doesn't elevate hormone levels above normal physiological ranges and will not accelerate hair loss beyond an individual's natural predisposition. Avoiding creatine for fear of hair loss is considered unwarranted by many experts.

Kidney and Liver Damage

Early concerns about creatine's effect on kidney and liver function have been largely debunked for healthy individuals. Extensive long-term studies have shown no significant negative effects on kidney health at recommended dosages. The misconception likely arose because creatine can cause a harmless, temporary elevation in creatinine levels, which is a marker sometimes used to assess kidney function. However, people with pre-existing kidney disease should exercise caution and consult a healthcare professional before starting creatine.

Side Effect Comparison: Standard Dose vs. High Dose

Side Effect Standard Dose (3-5g/day) High Dose/Loading Phase (15-25g/day)
Gastrointestinal Distress Rare and typically mild, if it occurs at all. More common occurrence of stomach cramps, bloating, and diarrhea.
Water Retention Gradual increase in water retention within muscle cells. More pronounced and rapid increase in water weight initially.
Dehydration Concerns Unlikely if adequate hydration is maintained. Increased risk if higher water demands are not met.
Effect on Hair No significant or proven impact on hair loss. No significant or proven impact on hair loss.
Kidney/Liver Strain Not a concern for healthy individuals. Not a concern for healthy individuals; requires more caution for those with pre-existing conditions.

Key Considerations for Safe Supplementation

To ensure creatine is used safely and effectively, follow these guidelines, many of which have been highlighted on the Huberman Lab:

  • Prioritize Creatine Monohydrate: It is the most studied and recommended form for both efficacy and safety.
  • Start with a Standard Dose: Begin with a consistent daily dose of 3-5 grams and skip the loading phase to minimize potential gastrointestinal issues.
  • Stay Hydrated: Always ensure you are drinking sufficient water, as creatine pulls more water into the muscles.
  • Listen to Your Body: Individual responses to supplements can vary, so it is important to pay attention to your own digestive tolerance.
  • Consult a Professional: Always talk to a healthcare provider before beginning any new supplement regimen, especially if you have pre-existing health conditions like kidney disease.

Conclusion

Dr. Andrew Huberman's recommendations regarding creatine are grounded in the extensive scientific literature surrounding creatine monohydrate. While some minor, dose-dependent side effects like gastrointestinal discomfort and water retention can occur, creatine is considered exceptionally safe and effective for the vast majority of healthy adults. The more severe risks often cited, such as hair loss or kidney damage, have not been substantiated by reliable evidence. By adhering to a standard daily dose and maintaining proper hydration, users can typically experience the benefits of creatine with minimal to no negative side effects.

This article is for informational purposes only and does not constitute medical advice. Please consult with a healthcare professional before beginning any new supplement regimen.

Frequently Asked Questions

No, Andrew Huberman does not recommend a specific brand of creatine. He advocates for creatine monohydrate in general, as it is the most researched and cost-effective form of the supplement.

The most common side effects associated with the creatine monohydrate recommended by Huberman are mild gastrointestinal distress (like bloating or diarrhea) and water retention within the muscles.

According to the Huberman Lab, the concern that creatine causes hair loss by increasing DHT levels is largely a myth. Dr. Huberman and guest experts have stated that the effect is minimal and not a significant reason to avoid the supplement.

For healthy individuals, extensive research has shown no significant negative effects on kidney function from creatine at recommended dosages. However, those with pre-existing kidney disease should consult a doctor before use.

No, creatine does not cause dehydration; it pulls water into the muscle cells. However, it's important to increase your overall water intake to ensure proper hydration, as creatine increases the demand for water within your body.

To prevent stomach upset, you can skip the initial loading phase and take a consistent daily dose of 3-5 grams. Splitting the dose or taking it with food can also help.

Yes, much of the initial weight gain from creatine is due to water being drawn into the muscle cells, a process called cell volumization. Over time, this effect can be compounded by increased lean muscle mass.

References

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Medical Disclaimer

This content is for informational purposes only and should not replace professional medical advice.